Anti-Ageing

Antioxidant SkQ1 delays sarcopenia-associated damage of mitochondrial ultrastructure.

Vays et al., (2014), Aging (Albany NY).6:140-8.

Reproducible effects of the mitochondria-targeted plastoquinone derivative SkQ1 on Drosophila melanogaster lifespan under different experimental scenarios.

Krementsova et al (2012), Biogerontology. 13:595-607

The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats.

Kolosova et al., (2012) Aging (Albany NY). 4:686-94.

Effect of plastoquinone derivative 10-(6'-plastoquinonyl) decyltriphenylphosphonium (SkQ1) on estrous cycle and 17?-estradiol level in rats.

Chistyakov et al (2012), Biochemistry (Mosc). 77:1382-6.

Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents.

Anisimov et al., (2011), Aging (Albany NY). 3:1110-9.

Reactive oxygen species produced in mitochondria are involved in age-dependent changes of hematopoietic and mesenchymal progenitor cells in mice. A study with the novel mitochondria-targeted antioxidant SkQ1.

Shipounova et al., (2010), Mech Ageing Dev. 131:415-21.

Effects of the mitochondria-targeted antioxidant SkQ1 on sexually motivated behavior in male rats.

Amstislavskaya et al., (2010) Pharmacol Biochem Behav. 96:211-6.

Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent involution of the thymus in normal and senescence-prone rats.

Obukhova et al., (2009), Aging (Albany NY),1:389-401.

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 5. SkQ1 prolongs lifespan and prevents development of traits of senescence.

Anisimov et al. (2008), Biochemistry (Mosc), 73:1329-42